Browsing by Author "Fotis, Christos"
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Article
Mechanical Compression Regulates Brain Cancer Cell Migration Through MEK1/Erk1 Pathway Activation and GDF15 Expression
Kalli, Maria; Voutouri, Chrysovalantis; Minia, Angeliki; Pliaka, Vaia; Fotis, Christos; Alexopoulos, Leonidas G.; Stylianopoulos, Triantafyllos (2019)Mechanical compression is a common abnormality of brain tumors that has been shown to be responsible for the severe neurological defects of brain cancer patients representing a negative prognostic factor. Indeed, it is of ...
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Article
Solid stress-induced migration is mediated by GDF15 through Akt pathway activation in pancreatic cancer cells
Kalli, Maria; Minia, Angeliki; Pliaka, Vaia; Fotis, Christos; Alexopoulos, Leonidas G.; Stylianopoulos, Triantafyllos (2019)Solid stress is a biomechanical abnormality of the tumor microenvironment that plays a crucial role in tumor progression. When it is applied to cancer cells, solid stress hinders their proliferation rate and promotes cancer ...